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Julio César Castellanos
Co-Founder & CEO at Fastfold, building AI agents for biotech and pharma. ⚛️ Lead Engineer at Thirdway Health, where I lead a small team scaling voice agents for medical practices. M.Sc. in Biomedical Engineering at Uniandes 🔬 researching in AI Drug Design with small peptides using Boltz-1, AlphaFold2 and Protein Language Models with LLMs.
Before that, I worked at Globant as a Python/Bioscientist, where I was part of the founding team of the Life Sciences Studio. My work included developing medical imaging with Nvidia Clara 🩻 for hospitals, and collaborating with Verily (an Alphabet company) on a FHIR implementation for Clinical Pathways.
Research
J Castellanos, G Raposo, L Antunez
G Raposo, J Castellanos, H Hernandez
L Antunez, J Castellanos, G Raposo, C Murga M.D.
Code
Forked version of PLA-Net Protein-Ligand Interactions with GraphConvolutional Networks for Interpretable Pharmaceutical Discovery. Re-trained with PyTorch and added Docker Support GPU and Huggingface Space 🤗 Huggingface link Original paper on Nature Scientific Reports - Ruiz Puentes, P., Rueda-Gensini, L., Valderrama, N. et al. Predicting target–ligand interactions with graph convolutional networks for interpretable pharmaceutical discovery. Sci Rep 12, 8434 (2022).
Improvements to run OpenFold with re-trained weights for AlphaFold2 and parallelized with 🐳 Docker and Local Notebook for interactive inference and metrics visualization for PLDDT and PAE. Local inference Notebook here. Ahdritz, G., Bouatta, N., Floristean, C. et al. OpenFold: retraining AlphaFold2 yields new insights into its learning mechanisms and capacity for generalization. Nat Methods 21, 1514–1524 (2024). https://doi.org/10.1038/s41592-024-02272-z
voyager-bot is a fun Arduino bot controlled from a web browser using Nodejs on Docker for Raspberry pi with live cam streaming. Won 1st and 2nd place in the Oklahoma State University's 2016 Mercyry Robotics Challenge. Slides